Actress Christina Applegate is in the hospital fighting an agonizingly painful, double kidney infection with intravenous antibiotics, she revealed Tuesday.

The “Married… with Children” alum first started feeling unwell while visiting family in Europe, she said on Tuesday’s edition of the podcast “MeSsy,” which she co-hosts with fellow actress and MS sufferer Jamie-Lynn Sigler, broadcasting from the hospital. While on the plane home, she said she decided to go straight to the hospital from the airport.

Applegate, who revealed her multiple sclerosis diagnosis in 2021, jokingly calls the hospital her “pied-à-terre,” given her frequent visits. Normally, she said on MeSsy, doctors give her meds and send her home. This time, Applegate demanded to be admitted.

“I’m staying here because I want answers,” Applegate said she told hospital personnel. “I want every test that you can possibly think of or ones that you haven’t even thought of, and I want them done.”

Doctors at first suspected a urinary tract infection, and on a previous hospital visit had even gone so far as to quiz Applegate on her wiping technique, double-checking that she went front to back.

“Like, what am I, back-wiping?” Applegate said on the podcast. “Like, seriously, I’m 53.”

The “Dead to Me” actress said she was painfully validated when she awoke with excruciating pain radiating from her right side — and thought her appendix was bursting.

“So much pain,” Applegate said. “I’m screaming, and they ordered me an emergency CT at 2 in the morning.”

That revealed an infection in her right kidney that later spread to her left side as well. Now, rather than trying to send her home, the hospital “won’t let me leave yet — because things are messy,” Applegate said. “Because of this kidney infection, I have to have intravenous antibiotics right now. And that’s where we’re at.”

Sigler noted that if Applegate hadn’t advocated for herself, “this could have been so much worse.”

Applegate assured listeners she’s going to be ok, even while admitting she was “holding in a bag o’ tears right now.”

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